Bloomage BioTechnology Corporation Limited (688363.SS) Bundle
Founded on January 3, 2000 by Zhao Yan and Ling Peixue in Jinan, Bloomage BioTechnology Corporation Limited has grown from its first production plant in 2005 into a publicly traded powerhouse (Shanghai Stock Exchange ticker 688363) that industrializes hyaluronic acid via microbial fermentation, supporting a global footprint with subsidiaries in the US, France, Japan and South Korea and serving more than 4,000 brands across 70+ countries; its ownership remains anchored by Zhao Yan's controlling stake through Huaxi Xinyu Investment Co., Ltd. at 58.93%, while the company-employing 4,444 staff with a 920-strong R&D team (20.7% of the workforce)-reported core revenue of 5.37 billion CNY in 2024 and net income of 174.27 million CNY, invests roughly 20% of annual revenue in R&D, has cut carbon emissions by 30% since 2020 with a 2030 target of 50%, and is shifting from a hyaluronic acid focus toward a global anti-aging omics strategy targeting aggressive international expansion and a 15% CAGR in overseas sales by 2026
Bloomage BioTechnology Corporation Limited (688363.SS): Intro
Bloomage BioTechnology Corporation Limited (688363.SS) is a China-based biopharmaceutical and biomaterials company focused on industrial-scale production of hyaluronic acid (HA) and other bioactive ingredients using microbial fermentation. Founded in Jinan, Shandong Province, Bloomage has grown from a local biotech startup into a vertically integrated manufacturer supplying pharmaceutical, medical device, cosmetic, and health-care markets worldwide.- Founded: January 3, 2000 (Jinan, Shandong Province) - founders Zhao Yan and Ling Peixue.
- Core technology: Microbial fermentation-based industrialization of hyaluronic acid and related bioactive substances.
- First major manufacturing milestone: Completion of first production plant in Jinan (2005).
- Global expansion milestone: U.S. subsidiary established in 2012 following FDA licensing activities.
- Capital markets milestone: Listed on the Shanghai Stock Exchange (STAR Market) in 2019 under ticker 688363.
- Workforce: 4,444 employees as of December 31, 2024.
| Item | Detail |
|---|---|
| Company name (ticker) | Bloomage BioTechnology Corporation Limited (688363.SS) |
| Founding date & place | January 3, 2000 - Jinan, Shandong Province, China |
| Founders | Zhao Yan; Ling Peixue |
| Key technology | Microbial fermentation for hyaluronic acid and bioactive ingredients |
| First plant | Jinan production plant completed in 2005 |
| International presence | U.S. subsidiary established in 2012 (post-FDA engagement) |
| Public listing | Shanghai Stock Exchange (STAR Market), 2019 - 688363 |
| Employees (2024-12-31) | 4,444 |
- Manufacturing: Large-scale fermentation, extraction, purification and downstream processing to produce HA of multiple molecular weights and derivative formulations.
- Product segments:
- Pharmaceutical-grade HA (injectables, ophthalmic, wound care)
- Medical devices and surgical consumables incorporating HA
- Cosmetic and aesthetic products (dermal fillers, skincare ingredients)
- Functional food and nutraceutical ingredients
- Sales channels: Direct sales to pharmaceutical and medical device manufacturers, B2B ingredient supply to cosmetics and food companies, and distribution partners domestically and internationally.
- R&D & quality: In-house R&D for strain development, process optimization and new formulations; regulatory engagement (including FDA interactions) to support exports and product approvals.
- Vertical integration: Controls upstream fermentation and downstream formulation/packaging to capture margin across the value chain.
- High-margin pharmaceutical and medical device applications (e.g., injectable HA for orthopedics and ophthalmology).
- Rapidly growing cosmetic/dermal filler markets in China and internationally.
- Long-term supply contracts with medical device manufacturers and ingredient customers.
- Export growth supported by regulatory approvals and overseas subsidiaries.
- Multiple production facilities with scalable fermentation capacity (expanded since 2005).
- Proprietary strains and process know-how for HA of varying molecular weights and purity grades.
- Quality and regulatory track record enabling entry into regulated markets (e.g., U.S.).
- Public listing on SSE (STAR Market) providing capital for expansion and R&D.
Bloomage BioTechnology Corporation Limited (688363.SS): History
Bloomage BioTechnology Corporation Limited (688363.SS) began as a specialized manufacturer and developer of hyaluronic acid (HA) and related biotech products, expanding from raw-material production into finished products for pharmaceutical, medical aesthetic and cosmetic markets. Its listing on the Shanghai Stock Exchange under ticker 688363 marked a transition to broader capital access and public scrutiny, enabling accelerated capacity expansion and R&D investment.- Public listing: Shanghai Stock Exchange, ticker 688363.SS.
- Market capitalization (as of 31 Dec 2024): ~21.62 billion CNY.
- Core business lines: HA raw materials, medical devices/consumables, aesthetic and cosmetic formulations, R&D and contract manufacturing.
| Item | Data / Note |
|---|---|
| Listing | Shanghai Stock Exchange (688363.SS) |
| Market Cap (31‑Dec‑2024) | 21.62 billion CNY |
| Largest shareholder | Zhao Yan - 58.93% (via Huaxi Xinyu Investment Co., Ltd.) |
| Other major holders | Guo Shoucheng - 7.16%; Guo Shoucheng (Shanghai) Health Industry Equity Investment Center (LP) - 7.16% |
| Share status | Publicly traded - diverse retail and institutional holders complementing controlling private stake |
- Ownership model: dominant controlling shareholder (Zhao Yan) combined with public float - allows concentrated strategic control while retaining capital-market funding and liquidity.
- Governance implication: majority control supports long-term planning; public listing imposes disclosure, minority protections and market discipline.
Bloomage BioTechnology Corporation Limited (688363.SS): Ownership Structure
Bloomage BioTechnology Corporation Limited (688363.SS) operates with a governance and ownership mix that supports its R&D-driven, customer-focused strategy. The company's mission centers on innovation in biotechnology and the development and application of bioactive materials, guided by values of sustainability, customer satisfaction, and strategic collaboration. Key metrics that reflect this mission and values:- R&D investment: ~20% of annual revenue allocated to research and development.
- Carbon emissions: 30% reduction achieved since 2020; target 50% reduction by 2030.
- Customer satisfaction: 90% customer satisfaction rate as of 2023.
- Research collaborations: Partnerships with 15 research institutions and 5 major universities.
| Metric | 2023 / Current | Target / Note |
|---|---|---|
| R&D spend (% of revenue) | ~20% | Maintained annually to drive product pipeline |
| Customer satisfaction | 90% | Ongoing customer-centric initiatives |
| Carbon emissions reduction (since 2020) | 30% | Target: 50% by 2030 |
| Academic & research partners | 15 institutions; 5 universities | Collaborative R&D and technology transfer |
- Core products: hyaluronic acid (HA) and related bioactive materials for cosmetic, medical, and industrial applications.
- Sales channels: direct B2B supply, branded consumer products, OEM/ODM partnerships and exports to international markets.
- Value drivers: proprietary fermentation and purification technologies, scaled production capacity, and IP licensing opportunities.
Bloomage BioTechnology Corporation Limited (688363.SS): Mission and Values
Bloomage BioTechnology Corporation Limited (688363.SS) operates a vertically integrated model spanning research, development, production and sales of bioactive materials, with hyaluronic acid (HA) as its core product. The company leverages microbial fermentation technology to produce sodium hyaluronate for medical, aesthetic and cosmetic applications, supplying injection-grade and cosmetic-grade HA to domestic and international markets.- Vertically integrated value chain: in-house R&D → pilot → large-scale fermentation → downstream purification → formulation → sales & distribution.
- Core technology: microbial fermentation platforms for high-purity hyaluronic acid production, enabling consistent molecular-weight control and scalability.
- Customer channels: direct sales to medical device and pharmaceutical manufacturers, contract manufacturing (OEM/ODM), branded cosmetics and aesthetic clinics, and export markets.
| Metric | Detail / Value |
|---|---|
| Major production sites | Jinan plant (53,334㎡) - injection-grade sodium hyaluronate; Jinan factory (140,000㎡) |
| Production capacity (end 2019) | 320 metric tons (hyaluronic acid) |
| R&D team | 920 personnel (20.7% of total workforce) |
| Estimated total workforce | ~4,444 employees (derived from R&D share) |
| International subsidiaries | United States, France, Japan, South Korea |
| Primary revenue streams | Injection-grade sodium hyaluronate sales, cosmetic HA derivatives, medical devices/components, OEM/ODM services, export sales |
- Bulk HA sales: high-purity sodium hyaluronate supplied to pharmaceutical and device manufacturers for injectable products and viscoelastic solutions.
- Finished products: branded dermal fillers, viscosupplements and cosmetic formulations sold through medical and retail channels.
- Contract manufacturing: producing HA intermediates and finished formulations for third-party brands (OEM/ODM).
- Export and channel expansion: revenue from subsidiaries and international distributors in the US, EU, Japan and South Korea.
- R&D intensity: a dedicated R&D team (920 people, ~20.7% of staff) focused on molecular-weight control, novel delivery forms and downstream purification to enhance product differentiation and margin.
- Quality systems: GMP-compliant production, quality control labs, and process validation to meet medical and cosmetic regulatory standards across export markets.
- Global presence: local subsidiaries to support clinical partnerships, regulatory filings and market development in key regions.
Bloomage BioTechnology Corporation Limited (688363.SS): How It Works
Bloomage BioTechnology Corporation Limited (688363.SS) operates as a vertically integrated manufacturer and supplier of hyaluronic acid (HA) and related bioactive materials, serving pharmaceutical, cosmetic, and food markets. Its operations combine upstream fermentation and bioprocessing with downstream purification, formulation, and global distribution.- Raw materials & bioprocessing: microbial fermentation to produce sodium hyaluronate (HA) at scale.
- Purification & quality control: multi-step purification, GMP/ISO-compliant facilities for pharmaceutical-grade output.
- Product formulation: conversion into pharmaceutical injectables, topical cosmetic solutions, and food-grade supplements.
- Sales & distribution: direct B2B sales to drug manufacturers, cosmetic brands, and nutraceutical companies; exports to Europe, North America, Japan, South Korea, and other markets.
- R&D & innovation: formulation, molecular-weight control of HA, biosafety testing, and new application development for sustained competitive advantage.
| Metric | 2024 | 2023 | YoY Change |
|---|---|---|---|
| Total Revenue (CNY) | 5.37 billion | 6.08 billion | -11.61% |
| Net Income (CNY) | 174.27 million | (2023) ~589.6 million | -70.59% |
| Core Product Lines | Pharmaceutical-grade sodium hyaluronate; Cosmetic-grade sodium hyaluronate; Food-grade sodium hyaluronate | ||
- Primary revenue drivers:
- Pharmaceutical sales: injectable HA for ophthalmic, orthopedics, and other medical uses (high-margin, regulated).
- Cosmetic sales: topical and injectable HA products for aesthetic medicine and mass-market skincare (volume-driven).
- Food & nutraceuticals: lower-margin, higher-volume dietary supplement HA products.
- Supporting revenue sources:
- Contract manufacturing and OEM supply agreements.
- Export sales and licensing partnerships in global markets.
Bloomage BioTechnology Corporation Limited (688363.SS): How It Makes Money
Bloomage BioTechnology generates revenue primarily by producing and selling hyaluronic acid (HA) and HA-based bioactive materials for cosmetics, pharmaceuticals, medical devices, and advanced regenerative applications. The company leverages upstream fermentation, downstream purification and proprietary formulation to capture value across product tiers-from bulk HA monomers to high-margin finished formulations and specialty medical-grade derivatives.- Global footprint: operations and sales in over 70 countries and regions, supplying more than 4,000 global brands.
- Product mix: bulk HA (commoditized, volume-driven), specialty HA derivatives (higher margin), finished cosmetic and medical products (brand-driven margins).
- R&D-driven pipeline: moving from HA-centric offerings to an anti-aging omics strategy (glycobiology, cell biology, regenerative medicine) to create new high-value products and platform technologies.
| Metric | Value / Target |
|---|---|
| Market capitalization (Dec 15, 2025) | 20.72 billion CNY |
| Market cap change (past 12 months) | -27.11% |
| Geographic presence | 70+ countries / regions |
| Brand customers | 4,000+ global brands |
| International sales CAGR target | 15% by 2026 |
| International market expansion (next 2 years) | Enter 3 new markets including North America and Europe |
| Strategic focus | Glycobiology, cell biology, regenerative medicine (anti-aging omics) |
- Revenue drivers:
- Volume sales of bulk HA to manufacturers (price and scale-sensitive).
- Higher-margin specialty HA derivatives sold to cosmetics and medical-device customers.
- Branded finished products and distribution partnerships for end-consumer sales.
- Licensing and collaboration revenues from platform technologies in regenerative and cell biology.
- Profitability levers:
- Vertical integration in fermentation and purification reduces COGS and protects margins.
- R&D-driven product differentiation to resist commoditization.
- Geographic mix shift toward higher-margin Western markets targeted by the company's expansion plan.

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