Compugen Ltd. (CGEN): ANSOFF Matrix Analysis [Jan-2025 MISE À JOUR]

Dans le paysage rapide de la biotechnologie et de l'intelligence artificielle, Compugen Ltd. (CGEN) est à l'avant-garde de la découverte révolutionnaire de médicaments, naviguant stratégiquement des opportunités de marché complexes grâce à une approche complète de la matrice d'Ansoff. En tirant parti des plates-formes de calcul de pointe et des algorithmes d'apprentissage automatique, la société est prête à transformer la façon dont les innovations thérapeutiques sont développées, ciblant non seulement les marchés existants, mais explorant les frontières sans précédent en médecine de précision, en traitements personnalisés et méthodologies de recherche avancées.

Compugen Ltd. (CGEN) - Matrice Ansoff: pénétration du marché

Augmenter les efforts de vente directe

Compugen a déclaré un chiffre d'affaires total de 5,2 millions de dollars pour le quatrième trimestre 2022, avec des partenariats pharmaceutiques générant 3,7 millions de dollars de revenus collaboratifs.

Élargir les campagnes de marketing

Les dépenses de marketing pour la plate-forme de découverte de médicaments dirigée par AI ont été de 2,1 millions de dollars en 2022, ce qui représente une augmentation de 40% par rapport à 2021.

• Budget de marketing numérique: 850 000 $
• Parrainages de la conférence scientifique: 450 000 $
• Publicité numérique ciblée: 800 000 $

Développer des stratégies promotionnelles

Le segment d'immuno-oncologie représentait 62% du pipeline de recherche de Compugen en 2022.

Améliorer la fidélisation de la clientèle

Le taux de rétention de la clientèle en 2022 était de 87%, avec une durée de partenariat moyenne de 3,4 ans.

Optimiser les stratégies de tarification

Les accords de recherche en collaboration étaient en moyenne de 1,2 million de dollars par partenariat en 2022, avec des paiements de jalons potentiels allant de 5 à 15 millions de dollars par programme.

Compugen Ltd. (CGEN) - Matrice Ansoff: développement du marché

Expansion internationale sur les marchés de la biotechnologie européenne et asiatique

Compugen Ltd. a déclaré un chiffre d'affaires total de 14,2 millions de dollars en 2022, avec des opportunités potentielles d'expansion du marché international en Europe et en Asie.

Cible les sociétés biopharmatiques émergentes

Marché de la plate-forme de découverte de médicaments informatiques estimé à 3,8 milliards de dollars en 2023.

• Les entreprises biopharmatiques émergentes représentent 62% du pipeline de découverte de médicaments
• Les plateformes de calcul réduisent les coûts de développement des médicaments de 40%
• Réduction moyenne de délai de marché: 3-4 ans

Partenariats stratégiques avec les institutions de recherche

Compugen maintient actuellement 3 collaborations de recherche internationale.

Approbations réglementaires dans des pays supplémentaires

Approbations réglementaires actuelles: États-Unis, Israël

• Examens réglementaires en attente dans 4 pays européens
• Processus d'approbation réglementaire estimé: 18-24 mois
• Accès supplémentaire sur le marché: 15% du marché mondial de la biotechnologie

Adaptation de marketing régional

Budget de localisation marketing alloué: 1,2 million de dollars en 2023

Compugen Ltd. (CGEN) - Matrice Ansoff: développement de produits

Investissez dans l'expansion des capacités de découverte de médicaments dirigés sur l'IA

Compugen a investi 23,4 millions de dollars dans les dépenses de R&D pour l'exercice 2022, en se concentrant sur les plateformes de découverte de médicaments informatiques. Le budget de recherche de l'entreprise a alloué 68% au développement technologique axé sur l'IA.

Développer de nouvelles plateformes de calcul pour la médecine de précision

La plate-forme de médecine de précision de Compugen cible 7 domaines thérapeutiques distincts avec une taille de marché potentielle estimée à 62,3 milliards de dollars d'ici 2025.

• Ciblage de précision en oncologie
• Développement d'immunothérapie
• Modélisation de calcul des maladies rares

Créer des outils de modélisation prédictive avancés

Les algorithmes de modélisation prédictifs de l'entreprise démontrent 34% d'identification des candidats médicamenteux plus rapide par rapport aux méthodes traditionnelles. Réduction du temps moyenne de 5,2 ans à 3,4 ans en découverte de médicaments à un stade précoce.

Améliorer les technologies de recherche sur les anticorps thérapeutiques

Compugen compte actuellement 3 candidats anticorps thérapeutiques en développement clinique, avec une évaluation potentielle du marché de 412 millions de dollars pour ces programmes.

Introduire des algorithmes d'apprentissage automatique

La mise en œuvre de l'apprentissage automatique a augmenté les taux de réussite de la découverte de médicaments de 22%, ce qui réduit les taux d'échec potentiels de 90% à 68% dans les processus de dépistage à un stade précoce.

Compugen Ltd. (CGEN) - Matrice Ansoff: diversification

Services de découverte de médicaments informatiques pour le secteur de la biotechnologie agricole

La plate-forme de découverte de médicaments de calcul de Compugen génère des revenus potentiels de 3,5 millions de dollars en recherche sur la biotechnologie agricole en 2022. La technologie de découverte de la société axée sur l'IA cible la protection des cultures et les solutions biologiques agricoles.

Opportunités du marché des technologies de la santé

Compugen a identifié 7,8 millions de dollars d'opportunités potentielles du marché du diagnostic grâce à des plateformes de biologie informatique en 2022.

• Valeur du segment du marché diagnostique: 45,2 milliards de dollars
• Investissement en technologie diagnostique dirigée par AI: 2,5 millions de dollars
• Pénétration potentielle du marché: 0,4%

Plateformes d'IA pour la recherche sur les maladies rares

Compugen a alloué 4,6 millions de dollars au développement de plateformes d'IA pour la recherche de maladies rares en 2022.

Acquisitions de technologie stratégiques

Compugen a évalué les acquisitions stratégiques potentielles avec une considération totale d'investissement de 12,3 millions de dollars dans des sociétés technologiques complémentaires en 2022.

• Budget total d'acquisition: 12,3 millions de dollars
• Nombre de sociétés cibles potentielles: 6
• Critères d'alignement technologique: 80% de correspondance de biologie informatique

Conseil de médecine de santé numérique et de précision

Compugen a étendu les services de conseil en santé numérique avec des investissements de 2,1 millions de dollars dans le développement de la technologie de médecine de précision.

Compugen Ltd. (CGEN) - Ansoff Matrix: Market Penetration

You're focused on maximizing the value of your current assets, which is exactly what Market Penetration is all about for Compugen Ltd. (CGEN). We're pushing hard to get the existing COM701 product into as many relevant patients as possible within the established markets.

The immediate action is driving enrollment in the MAIA-ovarian platform trial for COM701 maintenance therapy in patients with platinum sensitive ovarian cancer. This trial is actively enrolling across the U.S., Israel, and France. Remember, the pooled analysis from three Phase 1 trials, which included 60 evaluable patients, showed COM701 was well tolerated and delivered durable responses, with a median progression-free survival of 10.5 months in those patients who derived clinical benefit. That data is the fuel for this penetration strategy. We are looking for the projected interim analysis results from this trial around Q1 2027, though some internal estimates pointed to year end 2026.

For clinical visibility, the key near-term event isn't a conference presentation in 2026, but rather the data readout itself. The H2 2026 data from the COM701 MAIA-ovarian trial is the critical moment to boost clinical visibility and potentially secure better commercial positioning or partnership terms down the line. That's the real milestone you're aiming for right now.

The COM902 strategy feeds into Market Penetration via the partnership with AstraZeneca on rilvegostomig. Accelerating data generation for COM902 monotherapy is less about securing a Phase 3 partner for COM902 itself, and more about validating the Fc-reduced anti-TIGIT approach, which directly supports the value of the rilvegostomig program. AstraZeneca is supporting this with an expanding clinical footprint; they are now expected to launch their eleventh Phase 3 trial for rilvegostomig across various cancer types. Each successful trial completion helps trigger milestone payments, which are a direct financial return on this market penetration effort.

Financially, you're in a strong position to execute this penetration strategy without external dilution, at least for the near term. You need to leverage that balance sheet strength. The cash balance as of September 30, 2025, stood at approximately $86.1 million. Honestly, this gives you the runway to fully fund the COM701 MAIA-ovarian trial into Q3 2027, even without factoring in potential cash inflows from milestones, like the ones tied to the Gilead collaboration where you've already received $90 million and are eligible for an additional $758 million.

Here's a quick view of the key metrics supporting this current market focus:

To keep the execution tight, you should monitor these operational checkpoints:

• Confirm site activation rates in France for MAIA-ovarian.
• Track the pace of enrollment against the Q1 2027 interim analysis target.
• Review AstraZeneca's planned data updates for rilvegostomig at upcoming conferences.
• Ensure R&D expenses for Q3 2025, which were approximately $5.8 million, remain within budget.
• Monitor Q3 2025 revenue of approximately $1.9 million against prior year comparable periods.

Finance: draft 13-week cash view by Friday.

Compugen Ltd. (CGEN) - Ansoff Matrix: Market Development

You're looking at how Compugen Ltd. can take its existing, validated assets and push them into new markets or new indications, which is the essence of Market Development here. The financial footing supports this expansion, as of September 30, 2025, Compugen Ltd. held approximately $86 million in cash, cash equivalents, short-term bank deposits, and investment in marketable securities. This solid balance sheet is expected to fund operating plans into the third quarter of 2027.

Expand COM701's MAIA-ovarian platform trial to new high-incidence regions like Asia or Western Europe.

The current MAIA-ovarian platform trial for COM701, evaluating it as maintenance therapy for platinum-sensitive ovarian cancer, is enrolling patients across the U.S., Israel, and France. To expand this into new geographic markets, consider the existing disease burden. Globally, in 2020, there were 313,959 new cases of ovarian cancer recorded. For context on Western Europe, the proportion of Serous Carcinoma (SC), a major subtype, reached 57.69% of cases in that region in 2020. Conversely, Asia has shown increasing rates in certain countries between 2013 and 2017, and by 2050, the largest absolute increase in diagnosed women is projected to be in Asia. The interim analysis for the current COM701 sub-trial is estimated for Q1 2027, which provides a near-term data point before a major international rollout decision.

Initiate COM902 trials in combination with non-PD-1 checkpoint inhibitors for new solid tumor types.

COM902 is the underlying anti-TIGIT antibody licensed to AstraZeneca, which is being developed as the Fc-reduced bispecific rilvegostomig. The broader Solid Tumor Therapeutics Market size stood at $207.29 billion in 2025. Specifically, the Immune Checkpoint Inhibitors for Cancer market was projected to reach approximately $35,000 million by 2025. AstraZeneca is advancing rilvegostomig with ten active Phase 3 trials and expects to launch its eleventh Phase 3 trial. This existing infrastructure in solid tumors, where the Asia-Pacific region is forecast to grow at a 9.54% CAGR, provides a foundation for combination studies in new indications beyond the current focus areas.

Pursue a new licensing deal for COM902 in a specific, high-unmet-need cancer indication.

While existing deals are in place, the value proposition for COM902-derived assets remains high. Compugen Ltd. is eligible for mid-single-digit tiered royalties on rilvegostomig sales exceeding $5 billion. Furthermore, the company is eligible for over $1 billion in future milestones and royalties from the combined collaborations with AstraZeneca and Gilead. The GS-0321 (COM503) program, licensed to Gilead, is progressing, with its Phase 1 trial design presented at SITC 2025. The potential for a new deal would leverage the validated Fc-reduced mechanism, which Compugen Ltd. believes preserves beneficial T cells.

Utilize existing clinical trial infrastructure in the U.S. to launch new Phase 1 studies for proprietary assets.

The company's current financial stability is key to funding proprietary asset expansion. The cash balance as of June 30, 2025, was approximately $93.9 million, and the R&D expenses for Q3 2025 were approximately $5.8 million. The existing operational footprint, which includes enrolling patients in the U.S. for the MAIA-ovarian trial, can be leveraged. The company has no debt, which provides flexibility to initiate new Phase 1 studies without immediate external financing pressure, supported by the cash runway extending into Q3 2027.

• COM701 is an anti-PVRIG antibody.
• GS-0321 (COM503) is a potential first-in-class anti-IL18BP antibody licensed to Gilead.
• Rilvegostomig is an Fc-reduced PD-1/TIGIT bispecific antibody.
• Western Europe SC proportion in ovarian cancer was 57.69% in 2020.
• Asia-Pacific CAGR in solid tumor therapeutics is forecast at 9.54% through 2030.

The company sold approximately 0.8 million shares in October 2025, contributing net proceeds of approximately $1.6 million.

Compugen Ltd. (CGEN) - Ansoff Matrix: Product Development

You're looking at how Compugen Ltd. is pushing new products-their pipeline assets-into development, which is the core of the Product Development quadrant in the Ansoff Matrix. This is where the computational discoveries from the Unigen™ platform move from the lab bench toward the clinic, funded by their current financial position.

The commitment to this path is clear in the spending. Compugen Ltd. dedicated approximately $5.8 million to Research & Development in the third quarter of 2025. This spend supports advancing the pipeline, including pushing two new pre-clinical targets discovered via the Unigen™ platform further along, building on the success of their known candidates. Honestly, keeping that early-stage pipeline moving is the engine for future value, especially since their cash runway is currently projected to fund operations into the Q3 2027 timeframe.

A major focus remains on leveraging the existing clinical assets, COM701 and COM902, to create next-generation therapies. This involves developing novel bispecific or trispecific antibodies that combine one of these core molecules with a new target identified by Compugen Ltd. The strategy is already validated through partner AstraZeneca's rilvegostomig, an Fc-reduced PD-1/TIGIT bispecific whose TIGIT component is derived from COM902. That program alone has a non-risk-adjusted peak year revenue target estimated by AstraZeneca to be more than $5 billion. Compugen Ltd. retains the rights to develop its own bispecifics combining PVRIG (COM701) and TIGIT (COM902).

Translational research is key for de-risking the clinical path for COM701, the potential first-in-class anti-PVRIG antibody. The company is investing to identify new biomarkers that can pinpoint which patients will benefit most from COM701's differentiated PVRIG pathway blockade. This work directly informs the ongoing MAIA-ovarian platform trial, which is evaluating COM701 as maintenance therapy in relapsed platinum-sensitive ovarian cancer. The pooled analysis of 60 evaluable patients from Phase 1 trials in platinum-resistant ovarian cancer, presented at ESMO 2025, showed durable responses and supported this maintenance therapy rationale. You can expect the interim analysis for the MAIA-ovarian trial is now estimated for Q1 2027.

Also critical is the advancement of the early-stage myeloid programs, which the company views as a key value driver for pipeline growth. This involves moving these computationally discovered targets into formal pre-clinical development. For instance, Compugen Ltd. has a collaboration with Johns Hopkins University investigating a novel myeloid target discovered by their platform, which showed significant tumor growth inhibition in initial in-vivo studies. This is how you build out the pipeline beyond the current clinical assets.

Here's a quick look at the current development status of the key assets driving this product development strategy:

The R&D spend of $5.8 million in Q3 2025 is being allocated across these efforts, balancing the late-stage work on COM701 with the foundational work needed to bring the next wave of targets, including the myeloid programs, to the clinic.

The focus areas for advancing the pipeline are:

• Advance two new pre-clinical targets from the Unigen™ platform.
• Develop bispecifics combining COM701 or COM902 with new targets.
• Invest in translational research for COM701 biomarkers.
• Advance early-stage myeloid programs into formal pre-clinical development.

Finance: draft 13-week cash view by Friday.

Compugen Ltd. (CGEN) - Ansoff Matrix: Diversification

The Unigen™ platform, a proprietary, validated AI/ML powered system, is the engine for discovering novel drug targets and biological pathways. This platform is currently advancing immuno-oncology programs, but its technology-agnostic approach supports expansion into other areas.

The financial position as of September 30, 2025, provides the capital base to fund exploratory work in new therapeutic areas, such as autoimmune or infectious disease, without immediate reliance on new external funding for the research phase.

The existing partnership structure demonstrates the potential scale of future non-oncology deals. The current agreements with AstraZeneca and Gilead offer over $1 billion in potential milestone payments and tiered royalties, which sets a benchmark for potential upfront cash in a new, non-oncology discovery partnership.

Applying the Unigen™ AI/ML platform to discover targets outside of oncology, like autoimmune or infectious disease, is a direct diversification path. This effort is supported by the platform's ability to analyze diverse biological datasets, including multi-omics and spatially resolved transcriptomics modalities.

Seeking a new, non-oncology discovery partnership would aim for an upfront cash component, similar to the structure that contributed to past revenue recognition. For instance, the upfront payment from the Gilead license agreement was a significant component of prior period revenues.

Out-licensing the Unigen™ platform's computational capabilities for a fee-for-service model in a new therapeutic area represents a revenue diversification stream separate from drug discovery milestones. The platform's validated predictive computational process could be offered to entities outside of the core immuno-oncology focus.

Developing a proprietary cell therapy or vaccine based on a novel Compugen-discovered target is a higher-risk, higher-reward diversification from the current antibody-focused pipeline. The company's in-house assets include COM701 (anti-PVRIG) and COM902 (anti-TIGIT), both antibodies.

The current pipeline progress includes:

• COM701 median Progression-Free Survival (PFS) in benefiting patients: 10.5 months.
• Estimated interim analysis for the COM701 MAIA-ovarian trial: Q1 2027.
• GS-0321 (licensed to Gilead) Phase 1 trial recruitment ongoing as of Q3 2025.
• AstraZeneca's rilvegostomig program expanded to eleven Phase 3 trials as of November 2025.

The company has no debt, which provides financial flexibility to initiate research into these new modalities using the existing cash balance of $86.1 million as of September 30, 2025.